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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8452c8b0c8f35916fdeee77bf255fe8c0a0e1f8a3c2b054bb999b036a46d9616' 
  AND token = 'oFZMoOikV1OI+jtlwTAM83yJ0Yi3/BdFH6v8GQ62EIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}