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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50335ffc83c19c4b8a3b01f78e28116e40639b372e7913fbb3ac1996a60c7ca' 
  AND token = 'BokByt1Nxzh9yMuDXwQZQyD45Pwg/EetgzrxruPwkgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}