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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d072ba818a65fd92649036fb5f0e60b99bcf2b886787cc7f94b6679e63bc7a4' 
  AND token = '1Q++0mbpjpUl3f+nWBYX11bs/5v+gYYFcJiscWNqCbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}