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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b1d87e54161901f45d117a81e7143f38d37822236ba12da717490dc5050203' 
  AND token = 'f5yMGVckBByxY8Z7TOjrGIbhj+gfHK2VTH48JRXkXNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}