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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '884886b4ed4ad20ae6267eeeb21eeee8491bfbda72271d3462890c896e6558b3' 
  AND token = 'I0FjPa/LZX+8uzIBd6l7HzLuEllOM1Ed4PCSvFwR0gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}