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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2253effbb9cc5e76ebb10b2f5ae4363d0710226a377c0c33f61009ec59f1d6e5' 
  AND token = 'Dj1GfEvkGimBdmsHpn0pUCFhSoMIZf5sPSiCIJZKI/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}