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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78c3dc941d547814567182a9e7660096676d0a4829648dc48d5f073f6b3225c' 
  AND token = 'ZDmXZqR9eUirXrp96o4Q9CEUuowOBRAaW71X6q8N3VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}