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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35f4ebdd97a97c7d02df79047980ed42bd4ab838325a1e0da6c1ed018b1d56fd' 
  AND token = '+l/1ihL8mWPYMZbVc5FdxN8d3xmht7u7CrE4xxiS8B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}