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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743bb5099a8a009e0d6e98b8fd80ee594ad87da4344696779d634d31cf3ac7a6' 
  AND token = 'TQGWiAV1EyRuCKAcIhO8P/KJvmkxh1TttfczsL+M9ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}