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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58732385425201a05f93e5eb564dd7465b77337cda3d3af434af28788205a942' 
  AND token = '3byb54p+TL2t2iyDpropnyJmUERGBItTboUdQMd5v5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}