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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd746d68f37f14d7f0eefa4c459054f64824bbf5f521898e996236a2bcb2171df' 
  AND token = '4V4N5nGdb6MEF40eo66j23tN3Ydb5SEiUBn03fE/3wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}