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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e10f8663212ad8a950bb0806eddc727b25753a5058fc851a769fe444a18308' 
  AND token = 'ZWQ8pdq6aVDukx3WN5rwkkXaI+n7bG6fqTZfHp8RtU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}