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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19cb62da4540034412dfb2da78b6e1fcc6370acedfbd99f1f46ce8635c6f7bf0' 
  AND token = 'sAEDIhdcRcvc/vVV9W3ykRlZ9cesIBLAdoC3gOxJ9vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}