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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e649c3c51579a393aa8679de3ea5042a603afef3affa7f789b90f7418481729' 
  AND token = '6hkTicBEOH/j++EKs8dsjv7Ab+xcjOvJ4e4YgfXc3OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}