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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78e2335be8969632cf05e9bfa3c038f4cad86a5d21bbde3aa2c3b4756b57068' 
  AND token = 't2sCNppBr1YHC4ILSEhbbxDj45+EO1EWdO+6ZtV3BXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}