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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ac85583004c2f488868d5e267351b21c39e8d8f86e4d2d6ef15b9ff6359c15' 
  AND token = '3IWEdadFhAu+r/wBf1KxfNZTKY+afcaSPV6s7sTnXvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}