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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3248db2f4dda67fa83fe445bb79850b10b33c7ec470883cf96f252e75bd4880b' 
  AND token = 'WuHKPJ1MdJzkix6mQ2az7yXaR7+UluLd+fwPEnkpsA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}