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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd872a51fd9c3e0f865fb359880f65a4bb99f9022f510f5ee85531fbe9cf7f482' 
  AND token = 'IDZe0Usc+9nDbNkDEQGjK0/iUr1EUb4AEVqM9TGF0NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}