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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164726268e8028346e3d369a8eb4e2c5d1c1f8a7c6d0285d2df4b682d9df9ddb' 
  AND token = 'm+y/Hr7xt57140gt7Pw92d36fFB8uW1f6cCozvwvMeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}