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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ebc6203019c46b021492891932c6982c38f408c5e9e4c18385e21d74eebd9a0' 
  AND token = '3/0QG/QaOUtc1o2M/Xv1Rhh13w2ty1Fu03l5a+PvdDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}