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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de357582dbcdb5104fe872a05b099abe39866773192f48282573844c3625c3b' 
  AND token = '5+JqSniO5lXI0TMlZLK7fnuK/C0EKD72bfIoyMgIHHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}