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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b58a0a36f7b767407721a469abb91417491af46bbc4c63fae43919481e8b6a' 
  AND token = 'p+sKqtuwUgX/nzI+mf/D8y/NYMomYk2NEGzA07tNDC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}