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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d3a1e73c4d0b289e1e90107f9cc7656e6fd8d96e70c34a0cfbe0759bd1dde2' 
  AND token = 'r2/ki6uEvE9LS6saF+HjQ5eTYYAAJOm4mdLuXbchacI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}