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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c49c113c01aa261bdcb12ec8cffe384f4796d47aaf34169dcfa27ae252fa9a6' 
  AND token = 'JoDDXbrHmgcjaT1OhNohG/X62TMqU1yr9/CITr6NSxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}