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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264fb19f8ef2762327660e030bdba6f05ae188b787f936ef3f8298929c05d39c' 
  AND token = 'NXIoCSWrITbxCaFzzYiem7mwvEbjzm3c/tY0j7Hg3Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}