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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a5fe4e6e327bc0db2c9ffc8e9832d4b5b6ea3a0a6e5953e8546555a550c3d5' 
  AND token = 'IatYbTVtQwL23Jw5SgLO9jceXuma2UJESK7KP1GYkXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}