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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d8cb988fcb4a4e455281e5051109ba51f424fa224a73447f7d714c03f7321b' 
  AND token = '5o8KkxgR7Zw9APr+vc3tfqyD44ta3EeV3zJo6SB7F0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}