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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e25e07a3bc89fd3883abe82ea38612ff3fb3fe30362de1ec3fe8be992ac0906' 
  AND token = 'v53eQMyn4AAfKUDBE7ZbSliIGCFr0SvMGolwBsu+wRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}