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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0db68c84c3ae79cd2d5dfb07ff0ffb50b2611e182295bd5e214f1816de1922df' 
  AND token = 'w2nH4VVkwcgag3oPUQpLDRxMqKP3ZbO6wDdTKoahgFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}