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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a462ac3d694796dbb05ccce58188a6511c61af4ecf6a4a78a1dd1f5415b5ed4' 
  AND token = 'ZW1EJ84qO0vQ6P3ubkiEMI9xyEK/g+A8ay1rTT9rDis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}