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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2353d3cd287643f04170e2e012edfc187d5be0e97d83dda3b3cedae35772aa' 
  AND token = 'xTQw4t7DBFd/plFLTcwxNc6X1KF0CogUNPuvl+0LwMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}