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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5003622f395a019f2cc06735b99ead37e7bed978f8bf7489f9f5448b3464bad' 
  AND token = 'MSZiFbd4iNdW9XoR9fg2eqq4aFtgbJAEwEC6tL+2x9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}