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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '318abf6485b32201b4cd0a304051be61b0ba61b74093b2a8769ef763b38ec394' 
  AND token = '6/DjPL90rDulGn+6owlmOSqKvd4dgk7TOqRDBvKbeLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}