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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a10f83fc40aa445820586c63d9aab897f22ba6209b78484991d9246a1253f9c' 
  AND token = 'pC1X+F7bJKHTzgBNi1JEO8+LTGEia4UMoi6FSp2NIj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}