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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00e0672610d8bf559feb6aa57c8f8f249d67e97ca844bf2ff0166a117b1549d' 
  AND token = 'lfwjDmmpggedBx4rBiNrbC/uVGYnIzeQ7OyXbsASL40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}