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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47e054e8e49f97bcd08b6580e030f1d332597130b024501c8c3301b2d0a7d87e' 
  AND token = 'ZteGNB6nZqrzn6lglNdCmnSsMin+khTJXgJD1yfClw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}