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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d25fc9a2b5ab5e7217c21f52eeacdb8fae61ca51d90e1b043c2b97b3822e54d' 
  AND token = 'AJGxmmDzgkvNAyrMNDe/LT3awwep/F+osUvIj6lth3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}