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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8869d2a47de45bd0f03db8bc40453f6b45ea4e8118bca9255ff409c0e9b0641e' 
  AND token = 'lPrgobfMRpoMEfgIRRvOuoXF1btil8rad6uneeAkRqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}