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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21dc4fe35e7db254037bc32fa925a1e9a5341901fd16d0ce8792f67afffb1963' 
  AND token = '+hmQL3SqQhDp6h7vbyLxw4ZIC74TTCeo1/rCFWSWMUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}