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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a89c6da0a745e61f54be256d39aaea23c58bf92c70e023e4ca1b1deae4e928' 
  AND token = '+eTqB43cE5SC9/dv+Frgdk6Hnhp5xN2D1xNw8yo8QCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}