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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3a06fb56cb2cd598e8d3c05bf6cd721b256cffb13c80d32512d0f708af28ea' 
  AND token = 'IP+eH30KQyiXZ2lnIVxYrey3gANJIaC04eIvQybEOs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}