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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8151d10b6ce5a60e9806c803f495d7e783abd35d8eb9121e14c3b0c57a936a' 
  AND token = '6DqBCwzdGycjUw/G0EHxwxxaSSrDaWZJ4ocxkXNAmXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}