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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b022f3d9fa921f7f42d4f348b005102f06f5b197aff772d4d22c2d3faa89e31e' 
  AND token = 'JesdNj6Gcg7WqQuiqGRlNuF4NbAa13LyGDkw0wB9JoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}