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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200f41f5d34d0ef7b0630197ca8f3b2f6cc73ee9145d24be1a2dc25ceead5b67' 
  AND token = 'l+2RglhIYggXcNGEzXmOkGCR3K6MHaMTTLpXtwHW0GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}