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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce4c8fcf787348fbcf3481f27de10fe36473652378bd26a383424a924c152f3d' 
  AND token = '1XA0Yjn8KBmcHTZB2wPMgKvrkUSTnuVAxRx1k5tD5yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}