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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f237a3f1a5bdd464da2fa70fb1d51e0bf40395254fe7d5d00c2f0e67e1f385' 
  AND token = 'QISS7MQ7dwYdIoe57Mnk4xZHm0Rjbje2lv8z+WTTKCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}