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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04727c54a6e1f948ba8387bbda90f0385a920998038e3f3889483f25a6a8a05' 
  AND token = 'T2INCc3h2h7RYdgfcVm6l/Yn3iF3Ovhnfjl8FFyBmGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}