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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c9834bd6e5ca820d9bcaa2e7aae60d4d0a43d2bddc6b16327fff9ae9062157' 
  AND token = 'yo1BTHDKW+EU6fbaG8wrTcOrop6xdwi+pJzmxMTVNFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}