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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b1d542ea73453f6ae342c1b1dae2f1b2b25e8e2b5add859ba70c9cdb7188780' 
  AND token = 'cBXdd0+yplNgpbwhhXNKVp1H+BUrtu7NwuNtFVa0QI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}