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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c2b1956b192b84777607ef4eff72cb8c625753d63502c78587ec993658c13a' 
  AND token = 'H5aJHycVOQT/6KI6LQem2qRkAZHUH6Mcy1xMf/S+G8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}